Duphalac 667g/l Lactulose Oral Solution

Generic Name

Lactulose

About The Drug

Duphalac is a gentle laxative medicine that helps relieve constipation by softening the stool and making bowel movements easier. It also helps reduce harmful substances in the body in people with liver disease, which can improve symptoms of hepatic encephalopathy such as confusion or drowsiness. Because it works by drawing water into the bowel rather than irritating it, it is often used when a mild, effective option is needed for long-term bowel regularity.

Indications

When do you need this medication?

* Constipation: Helps soften hard stools and stimulate regular bowel movements when you are having trouble passing stool.

* Hepatic encephalopathy: Used in people with liver disease to lower ammonia levels in the blood and help reduce symptoms such as confusion, sleepiness, or changes in thinking.

* Preventing constipation-related discomfort: May help reduce bloating, straining, and discomfort caused by infrequent bowel movements.

Dosage and Administration

How to use the drug safely and effectively?

* Usual Dosage:

* For constipation in adults: The usual starting dose is often 15–45 mL per day, followed by a maintenance dose of 15–30 mL per day based on response.

* For children: The dose depends on age and should be determined by a doctor. Do not give to infants or children without medical advice.

* For hepatic encephalopathy in adults: Doses are usually adjusted by the doctor to produce 2–3 soft stools per day.

* Method of Administration:

* Take by mouth, usually once daily or in divided doses as directed by your doctor.

* You may take it with or without food.

* It can be taken straight from the bottle or mixed with water, juice, or milk to improve the taste.

* Measure the dose carefully using an oral measuring cup or spoon.

* Drink enough fluids during the day unless your doctor tells you otherwise.

* It may take 1 to 2 days to start working for constipation.

Side Effects

What may happen while using this medication?

* Common side effects:

* Bloating

* Gas

* Stomach cramps

* Nausea

* Diarrhea, especially if the dose is too high

* Less common but important side effects:

* Vomiting

* Severe diarrhea leading to dehydration

* Dizziness or weakness

* Low blood salts if used in high doses for a long time

Warnings and Precautions

What should you be careful about?

* Do not use this medicine if you are allergic to lactulose or any of its ingredients.

* Tell your doctor if you have:

* Diabetes

* Lactose intolerance

* A history of bowel blockage

* Unexplained abdominal pain

* If you develop severe diarrhea, stop using it and contact your doctor, as this can cause dehydration.

* For people using it for liver-related brain symptoms, follow the doctor’s instructions closely and do not change the dose on your own.

* This medicine contains sugars and may affect blood sugar control in some patients.

Drug Interactions

What medicines may interact with this drug?

* Antacids: May reduce the effect of lactulose if taken at the same time.

* Other laxatives: May increase the chance of diarrhea or dehydration.

* Medications affected by changes in potassium: If diarrhea becomes severe, low potassium may affect the safety of some medicines, especially heart medications.

* Always tell your doctor or pharmacist about all prescription medicines, over-the-counter products, and herbal supplements you use.

Storage

How should you store this medication?

* Store at room temperature.

* Keep the bottle tightly closed and protect it from excessive heat and direct light.

* Do not freeze.

* Keep out of reach of children.

* Check the label for the expiry date and do not use the medicine after it has expired.

## Additional Helpful Information

* If you miss a dose, take it when you remember unless it is almost time for the next dose.

* Do not take extra medicine to make up for a missed dose.

* If constipation lasts for more than a few days or if you have blood in the stool, severe pain, or vomiting, seek medical advice.

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